| "It was not so difficult to invent a new basic | | | | the liquid phases used in the given analysis is increased. |
| technology of Chromatography - Chromabarography; it | | | | At the same time low working temperatures may |
| is rather difficult to wait for its wide practical use for | | | | become necessary for certain thermally unstable |
| the development of science in the benefit of mankind!" | | | | samples (increase in column service time); |
| Aram Hayrapetyan | | | | As the peak height is related with carrier-gas rate, |
| There are the best chromatographs in the world, the | | | | wide peaks eluted later will be much sharper. This |
| most modern technological elaborations, but there is | | | | allows a better identification of low concentrations |
| not the one, which provides the maximum efficiency of | | | | (increase in analysis accuracy); |
| the chromatographic column. | | | | Attainment of symmetrical peaks also in case of |
| I have a lot of secrets in the field of chromatography! | | | | nonlinear adsorption isotherm, as the rear of the band |
| One of them is the attainment of maximum possible | | | | is at a higher pressure than the front; |
| efficiency of the chromatographic column | | | | The substantial enrichment, the increase in |
| (HAYRAPETYAN'S Effect). | | | | concentration of the component in the center of the |
| It is provided with new basic technology of | | | | band is conditioned by the compression of the band |
| chromatography - CHROMABAROGRAPHY (Russia | | | | both as a consequence of the moving pressure |
| patent "Chromatograph of A. S. Hayrapetyan"). | | | | gradient compared with the initial sorption pressure, and |
| The essence of the new basic technology of | | | | as a consequence of the presence of the moving |
| chromatography - chromabarography is the provision | | | | gradient of the optimal linear speed accompanying the |
| of the optimal conditions of the analysis by keeping | | | | band of components being analyzed from the inlet to |
| unchanged the linear rate of an imaginary point - the | | | | the outlet of the chromatographic column during the |
| zone of the sample moved in time by the carrier-gas | | | | while analysis cycle (increase in the efficiency of the |
| from the inlet to the outlet of the chromatographic | | | | separation of the components); |
| column, ∆ p being kept constant at its ends | | | | The pressure of the gas in the column can be |
| during the whole cycle of the analysis, by which a | | | | changed almost instantaneously and equilibrium can be |
| maximum column efficiency (Hayrapetyan's Effect) is | | | | attained in a very short time. Pressure re-regulation |
| attained. | | | | excludes the necessity of long "periods of cooling" of |
| What is Chromabarography? | | | | the column (express - analysis, economy of electricity), |
| The answer may be so: Or . . . so: | | | | while temperature increase programming may either |
| The main advantages of the proposed technology in | | | | cause evaporation of the stationary phase, which "flies |
| practical analysis may be generated in the form of the | | | | out" of the column, or destroy it chemically to various |
| following propositions: | | | | molecules, which also will soon come out by the |
| Attainment of maximum possible efficiency of the | | | | carrier-gas. The repetitive cycles of heating and cooling |
| column on account of providing the optimal conditions | | | | may cause compression of solid support particles |
| of the analysis by keeping unchanged the linear rate of | | | | during expansion, followed by destruction (crumbling) |
| an imaginary point - the zone of the sample moved in | | | | during compression, which leads to a progressive |
| time by the carrier-gas from the inlet to the outlet of | | | | change of permeability. |
| the chromatographic column; | | | | The maximumpossibleeffectivityof |
| Reduction of analysis time for a wide range of | | | | thechromatographiccolumn - |
| mixtures, which allows to work with a shorter column | | | | Hayrapetyan's Effect |
| (economy of solid support, liquid phase, column | | | | The maximum possible effectivity of the |
| material) and at much lower temperatures (economy | | | | chromatographic column - Hayrapetyan's E ff e c t |
| of electricity) for which the relative retention is | | | | All the rest - XX century. |
| generally high. Thus the best separation is attained | | | | P. S. |
| without increasing the analysis time. This means an | | | | C h r o m a b a r o g r a p h y |
| increase in the productivity of routine analyses and | | | | A new step of effectivity, |
| elaboration of chromatographic methods; | | | | A first - hand new technology. |
| Due to the fact that it is possible to work at lower | | | | Toward the new century with a new technology. |
| temperatures (economy of electricity) the amount of | | | | |